PT-141 - Renewal Hormone Center

What is PT-141?

PT-141 is a synthetic peptide drug developed by Palatin Technologies and licensed to Valeant Pharmaceuticals (now Bausch Health) under the brand name Vyleesi. It is an analog of the peptide melanocortin which activates central melanocortin receptors involved in sexual arousal and desire pathways in the brain.

Some key facts about PT-141:

• It is administered as a subcutaneous injection or nasal spray approximately 45 minutes prior to anticipated sexual activity to help treat low libido and improve sexual arousal in premenopausal women.
• Unlike medications like Viagra which act on peripheral systems to improve genital blood flow and response, PT-141 directly targets the central nervous system pathways that modulate sexual desire and motivation.
• Clinical trials have shown that women taking PT-141 experience significant improvements in levels of sexual desire, arousal, lubrication, and overall sexual satisfaction.
• As of 2019, PT-141 (Vyleesi) was FDA-approved to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women.
• Side effects are generally mild but may include nausea, flushing, headache and injection site reactions. More serious but rare side effects can include darkening of skin moles, skin darkening, sleep apnea, and suicidal thoughts.

So in summary, PT-141/Vyleesi is considered an important new treatment option for premenopausal women suffering from low libido and sexual dysfunction. Though not as well known as medications like Viagra and Cialis, targeted drugs like PT-141 that modulate central pathways of desire and motivation could represent the future of pharmacotherapy for many women struggling with sexual health concerns.

If you are struggling with a lack of libido or sexual satisfaction, consult our experienced physicians at Renewal Hormone Center Therapy Clinic to see if PT-141 is right for you. With customized treatment plans catered to your unique needs, we can help you reclaim a satisfying sex life and relationship happiness. Call today to schedule a private consultation!